why and how ELISA testing can be/is being used for COVID-19 serological antibody testing

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    Covid-19diagnostictesting,antibodytesting,andtracing,areregardedas
    key to reopening countries currently dealing with the coronavirus pandemic. Your assignment is to research current scientific literature and write a paper (about 10 pages, references included, double-spaced, 1-inch margins, 12 point font) dealing with why and how ELISA testing can be/is being used for COVID-19 serological antibody testing.

    Considerations for your paper:
    Style of assay- ELISA vs.lateral flow immunoassay
    ELISA antibody testing vs. diagnostic antigen testing.
    Significance of isotype detection: IgM vs. IgG, and timing
    Antigen choice for the assay
    Distinction between presence of antigen-specific antibodies and immunity
    Specificity-The SARS-CoV-2 virus that causes Covid-19, as well as SARS,
    MERS, and the common cold, are all coronaviruses – how would an ELISA test
    distinguish among exposure to them
    Test accuracy-sensitivity vs. specificity
    -Bayes Theorem as applies to test sensitivity and specificity -How might one arrive at a prior hypothesis?
    -Random vs. non-random sample testing in evaluating the assay -Effect of the frequency of a disease in the population
    You must properly reference your work:
    -References should primarily be from the scientific literature. -Given how recent this disease is you may use article preprints or
    postings on medRxiv and bioRxiv.
    -Any other non-journal references should be from reputable sources,
    e.g., Stat.
    -Reputable mainstream news sources, e.g., New York Times articles, may
    be helpful as a secondary source to lead you to a primary scientific source.
    Notewell:
    This is a scientific paper – do not include political or fringe points of view.

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